Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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901 – 915 of 5,529 results

901

TARGETMOL CHEMICALS INC YKL-06-062 5MG

502694129 YKL-06-062 5MG

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902

TARGETMOL CHEMICALS INC FLUDIOXONIL 5MG

502694041 FLUDIOXONIL 5MG

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903

TARGETMOL CHEMICALS INC TN1 5MG

502694092 TN1 5MG

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904

Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 100.0% | 664.70 | 1 G

Firmonertinib mesylate is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. It effectively inhibits EGFR active mutations and the T790M acquired resistant mutation, making it a valuable compound for cancer research, particularly for advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.

Orally active
Mutant-selective
Blood-brain barrier penetrant EGFR inhibitor
Inhibits EGFR active mutations
Inhibits T790M acquired resistant mutation
Potential for cancer diseases research
Especially for advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation

Pricing & Availability

905

Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 99.9% | 664.70 | 25 MG

Firmonertinib mesylate is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. It inhibits EGFR active mutations and the T790M acquired resistant mutation. This compound has potential for research into cancer diseases, particularly advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.

Orally active
Mutant-selective
Blood-brain barrier penetrant EGFR inhibitor
Inhibits EGFR active mutations
Inhibits T790M acquired resistant mutation
Potential for research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation

Pricing & Availability

906

eMolecules 24730-10-7 | Medchem Express | Dihydroergocristine (mesylate) | 5mg | 489863296 | HY-N2319 | MFCD00153792 | 707.84 | C36H45N5O8S

Pharmablock | 26-dichloro-4-methyl-3-nitro-pyridine | 500mg | 551319498 | PB03300 | 60010-03-9 | MFCD11110694 | 207.010 | C6H4Cl2N2O2

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
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907

Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 10MG

Dosimertinib-d5 mesylate is the deuterated mesylate salt of dosimertinib, a third-generation epidermal growth factor receptor (EGFR) inhibitor. Provided as a research-grade reference standard for preclinical and analytical applications; not for human or veterinary use.

Deuterated internal standard for analytical assays and mass spectrometry.
High purity: 99.4%.
Molecular formula: C29H32D5N7O5S.
Available in small pack sizes (1-100 mg) suitable for method development.
Mesylate salt form for improved handling and stability.

Pricing & Availability

908

Medchemexpress LLC Almonertinib mesylate | 2134096-06-1 | 99.7% | 621.75 | 25 MG

Almonertinib mesylate (HS-10296 mesylate) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows great inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). It is used for the research of non-small cell lung cancer, and can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R, and L861Q.

Orally available
Irreversible
Third-generation EGFR tyrosine kinase inhibitor
High selectivity for EGFR-sensitizing and T790M resistance mutations
Great inhibitory activity against T790M, T790M/L858R and T790M/Del19
Used for research of non-small cell lung cancer
Inhibits EGFR sensitive mutations (G719X, del19, L858R, L861Q)

Pricing & Availability

909

Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML

Trovafloxacin mesylate is the mesylate salt of trovafloxacin, a broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV. It is used in research to study antibacterial activity and pannexin 1 (PANX1) channel function and inhibition.

Broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV.
Also reported as a pannexin 1 (PANX1) inhibitor with an IC50 around 4 μM.
Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for experimental flexibility.
High purity: 99.8% (HPLC) as reported by supplier.
CAS number 147059-75-4; molecular weight 512.46 g/mol.

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910

Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | 99.9% | 25 MG

Danofloxacin mesylate is a fluoroquinolone veterinary drug known for its broad-spectrum bactericidal activity. It primarily functions by inhibiting the DNA gyrase of bacteria and also acts as a substrate for ATP-dependent efflux transporters such as P-gp and MRP2. This compound is intended for research use only.

Fluoroquinolone veterinary drug
Broad-spectrum bactericidal activity
Inhibits bacterial DNA gyrase
Substrate for ATP-dependent efflux transporters (P-gp and MRP2)
Exhibits asymmetric transport across Caco-2 cells
Inhibits bovine bacterial respiratory pathogens

Pricing & Availability

911

Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | MFCD00069218 | 100.0% | 750.70 g/mol | C33H44BrN5O8S | 5 MG

Bromocriptine mesylate is the methanesulfonate salt of bromocriptine, a semisynthetic ergot-derived dopamine D2/D3 receptor agonist used in research. It shows high affinity for D2 receptors (pKi ≈ 8.05) and is provided as both a solid and solution format for laboratory and analytical applications.

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912

Medchemexpress LLC Deferoxamine (mesylate) (Standard) | 138-14-7 | 99.8% | 25 MG

Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator that binds to Fe(III) and many other metal cations. It is widely used to reduce iron accumulation and deposition in tissues. It upregulates HIF-1α levels with good antioxidant activity and also shows anti-proliferative activity, inducing apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases, as well as anti-cancer and anti-COVID-19 research.

Binds to Fe(III) and many other metal cations.
Reduces iron accumulation and deposition in tissues.
Upregulates HIF-1α levels.
Exhibits good antioxidant activity.
Shows anti-proliferative activity.
Induces apoptosis and autophagy in cancer cells.
Used in studies of diabetes and neurodegenerative diseases.
Used in anti-cancer and anti-COVID-19 research.

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913

Cayman Chemical DeferoxamInmesylate 1g

A bacterial siderophore that chelates iron; used experimentally to inhibit iron-dependent prolyl hydroxylases (EC50 = 17.8 µM), thus preventing the degradation of isoforms of HIF during normoxia

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914

Medchemexpress LLC Phentolamine mesylate | 65-28-1 | 99.9% | 500 MG

Phentolamine mesylate is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptors. It expands blood vessels to reduce peripheral vascular resistance and can be used for the research of pheochromocytoma-related hypertension, heart failure, and erectile dysfunction.

Reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptors
Expands blood vessels to reduce peripheral vascular resistance
Used for research in pheochromocytoma-related hypertension, heart failure, and erectile dysfunction
High purity of 99.9%

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915

Medchemexpress LLC Deferoxamine mesylate (standard) | 138-14-7 | 99.47% | 50 MG

Deferoxamine mesylate (Standard) is an analytical standard intended for research and analytical applications. It functions as an iron chelator, binding to Fe(III) and other metal cations, thereby reducing iron accumulation and deposition in tissues. This compound also upregulates HIF-1α levels and exhibits good antioxidant activity, along with anti-proliferative activity that can induce apoptosis and autophagy in cancer cells.

Used in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research
Serves as a reference standard for assays
Frequently utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS

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Quinolines and derivatives

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Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 100.0% | 664.70 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 99.9% | 664.70 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Almonertinib mesylate | 2134096-06-1 | 99.7% | 621.75 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.8% | 512.46 g/mol | C21H19F3N4O6S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | MFCD00069218 | 100.0% | 750.70 g/mol | C33H44BrN5O8S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Deferoxamine (mesylate) (Standard) | 138-14-7 | 99.8% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Phentolamine mesylate | 65-28-1 | 99.9% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Deferoxamine mesylate (standard) | 138-14-7 | 99.47% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More